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"Initial sequencing and comparative
analysis of the mouse genome,"
by R.H. Waterston and 222 others
(Mouse Genome Sequencing Consortium), Nature, 420(6915): 520-62, 5
December 2002.
[Authors' affiliations: 46 institutions
worldwide]
Abstract: "The sequence of the
mouse genome is a key informational tool for understanding the contents of the
human genome and a key experimental tool for biomedical research. Here, we
report the results of an international collaboration to produce a high-quality
draft sequence of the mouse genome. We also present an initial comparative
analysis of the mouse and human genomes, describing some of the insights that
can be gleaned from the two sequences. We discuss topics including the
analysis of the evolutionary forces shaping the size, structure and sequence
of the genomes; the conservation of large-scale synteny across most of the
genomes; the much lower extent of sequence orthology covering less than half
of the genomes; the proportions of the genomes under selection; the number of
protein-coding genes; the expansion of gene families related to reproduction
and immunity; the evolution of proteins; and the identification of
intraspecies polymorphism."
This 2002 report from Nature was cited
91 times in current journal articles indexed in the Thomson Scientific
database during July-August 2004. For the fourth bimonthly period in a row,
this paper registered as the most-cited paper in biology, aside from reviews,
published in the last two years. Prior to the most recent two-month count,
citations to the paper have accrued as follows:
May-June 2004: 55 citations
March-April 2004: 98
January-February 2004: 87
November-December 2003: 73
September-October 2003: 62
July-August 2003: 76
May-June 2003: 38
March-April 2003: 31
January-February 2003: 15
November-December 2002: 1
Total citations to date: 627
SOURCE: Hot
Papers Database (Included with a subscription to the ISI print newsletter Science
Watch®, available from the ISI
Research Services Group. Packaged on a CD-ROM that is mailed with each Science
Watch issue, the Hot
Papers Database contains data on hundreds of highly cited papers published
during the last two years. User interface permits searching by author,
organization, journal, field, and more. Total citations, as well as citations
accrued during successive bimonthly periods, can be assessed and graphed. An
updated CD containing the most recent bimonthly data is mailed with every new
issue of Science
Watch,
six times a year. The CD also includes an electronic version of the Science
Watch
issue in HTML format, for personal desktop access.)
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