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"The DNA sequence of human chromosome
22," by I. Dunham and 220
others, Nature, 402(6761):489-95, 2 December 1999.
[Authors' affiliations: 10 institutions
worldwide]
Abstract: "Knowledge of the
complete genomic DNA sequence of an organism allows a systematic approach to
defining its genetic components. The genomic sequence provides access to the
complete structures of all genes, including those without known function,
their control elements, and, by inference, the proteins they encode, as well
as all other biologically important sequences. Furthermore, the sequence is a
rich and permanent source of information for the design of further biological
studies of the organism and for the study of evolution through cross-species
sequence comparison. The power of this approach has been amply demonstrated by
the determination of the sequences of a number of microbial and model
organisms. The next step is to obtain the complete sequence of the entire
human genome. Here we report the sequence of the euchromatic part of human
chromosome 22. The sequence obtained consists of 12 contiguous segments
spanning 33.4 megabases, contains at least 545 genes and 134 pseudogenes, and
provides the first view of the complex chromosomal landscapes that will be
found in the rest of the genome."
This 1999 report from Nature was cited
37 times in current journal articles indexed in the ISI database
during July-August 2000. Aside from reviews, no other paper published in
biology in the last two years attracted more citations during that two-month
period. Prior to the most recently bimonthly count, citations to the paper
have accrued as follows:
May-June 2000: 16 citations
March-April 2000: 6
January-February 2000: 2
Total citations to date: 61
SOURCE: Hot
Papers Database (Available from the ISI
Research Services Group in a CD-ROM version containing data on
hundreds of highly cited papers published during the last two years.
User interface permits searching by author, organization, journal,
field, and more. Total citations, as well as citations accrued during
successive bimonthly periods, can be assessed and graphed. Database is
combined with subscription to the ISI newsletter Science
Watch®; updated discs containing the
most recent bimonthly data are mailed with each new issue, six times a
year.)
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