|
|
Alfred G. Knudson, Jr.
|
|
Senior Advisor to the President and Fox Distinguished
Scientist
Fox Chase Cancer Center
Philadelphia, PA USA |
|
and |
|
|
| Bert Vogelstein
[see
also] [see
also] [see
also] [see also]
[see
also] |
|
Professor of Oncology and Pathology
with a Joint Appointment in Molecular Biology and
Genetics
The Sidney Kimmel Comprehensive Cancer Center at
Johns Hopkins University
Baltimore, MD USA
and
Howard Hughes Medical Institute Investigator |
|
and |
|
|
| Robert A. Weinberg
[see
also] [see
also] [see
also] [see
also] |
|
Daniel K. Ludwig and American Cancer Society Professor
for Cancer Research
MIT
Cambridge, MA USA
and
Member
Whitehead Institute
Cambridge MA USA |
|
|
"For the discovery and elucidation of the role of
tumor suppressor genes in oncogenesis" |
|
|
| Comment: Knudson was the
trailblazer, in 1971, in this field, and Weinberg the discoverer of the first
tumor suppressor gene (Rb), involved in the development of retinoblastoma.
Vogelstein, the most-cited scientist of the last two decades, explained in the
late 1980s and early 1990s the multistep process of colon cancer which involves
the tumor suppressor gene p53. This prize would form a "bookend" of
sorts to the 1989 Nobel for work on oncogenes, given to Harold E. Varmus and J.
Michael Bishop. |
|
|
- -
- - -
OR - - - - - |
|
| Sir Michael J.
Berridge, FRS [see
also] [see
also] [see
also] [see
also] [see also] [see
also] [see
also]
|
|
Deputy Scientific Director and
Head, Molecular Signalling
The Babraham Institute
Babraham
Cambridge CB2 4AT UK
and
Honorary Professor Department of Zoology
University of Cambridge
Cambridge CB2 1TN, UK |
|
and |
|
|
| Yasutomi Nishizuka
[see
also] [see
also] [see
also] [see
also] [see also] [see
also] |
|
President Emeritus of Kobe
University
and
Formerly Professor and Chairman, Department of Biochemistry
School of Medicine
Kobe University
Kobe, Japan |
|
|
"For breakthrough contributions in cell signaling
that revealed two fundamental biochemical processes—Berridge for research on the second messenger inositol trisphosphate and
Nishizuka for the discovery and analysis of protein kinase C." |
|
|
|
Comment: This seems a
long overdue prize. Both discoveries – representing some of the most-cited
research reports of the 1980s and early 1990s – revealed basic biochemical
mechanisms. The influence of these findings, which are related, is vast, has
touched the work of researchers in many fields, and continues strongly to this
day.
|
|
|
- - - - - OR - - - - -
|
|
Francis S. Collins
[see
also] [see also]
|
|
Director, National Human Genome Research Institute
Senior Investigator
Genome Technology Branch
National Institutes of Health
Bethesda, MD USA
|
|
and |
|
|
|
Eric S. Lander
[see
also] [see
also] [see
also]
|
|
Professor of
Biology
MIT
Camrbidge
MA, USA
and
Director of the Whitehead Institute/MIT Center for
Genome Research
Whitehead Institute
Cambridge, MA USA |
|
and |
|
|
|
J. Craig Venter
[see
also]
|
|
President
The Center for Advancement of Genomics (TCAG)
Institute for Biological Energy Alternatives (IBEA), and
Venter Science Foundation
Rockville, MD USA |
|
|
"For contributions to mapping the human genome"
|
|
|
| Comment: An obvious
choice, but supported by ISI’s indicators of influence (citations) and,
logically, by the tremendous potential for clinical advancements of many
diseases that this work portends. |
|
|
Other Links |
|
- The 100 Most-Cited Scientists in Biology
& Biochemistry, Chemistry,
Economics
& Business, Immunology,
Microbiology, Molecular
Biology & Genetics, Neuroscience,
and Pharmacology &
Toxicology and Physics
from ISI
Essential Science Indicators
Web product, January 1993 - June 30, 2003.
- The 100 Most-Cited Scientists for the period
1981-1990, based on data from ISI’s Science Citation Index.
- List of Clinical
Medicine
researchers in ISIHighlyCited.com.
|
Chemistry
| Economics
| Physiology or Medicine | Physics
| 2003 Nobel Opening Page
Return
to previous page
| View Nobel Prize
Picks for: 2002 | 2003
|
cites
